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  metatag-keywords=(Fragilité)

  metatag-og:title=(Changes in frailty based on minimally important difference and the impact of spironolactone on frailty in heart failure with preserved ejection fraction: insights from the TOPCAT trial. Tang Y, et al, Open Heart 2025.)

  metatag-description=(Traduction du résumé de l'article : Changes in frailty based on minimally important difference and the impact of spironolactone on frailty in heart failure with preserved ejection fraction: insights from the TOPCAT trial. Tang Y, et al, Open heart 2025.)

  metatag-og:type=article
  metatag-article:published_time=2026-03-20
  metatag-article:modified_time=2026-03-20

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{{pmid>addtt:41125402|Changes in frailty based on minimally important difference and the impact of spironolactone on frailty in heart failure with preserved ejection fraction: insights from the TOPCAT trial.}}
{{pmid>addhash_fr:41125402|Fragilité}}

====== Changes in frailty based on minimally important difference and the impact of spironolactone on frailty in heart failure with preserved ejection fraction: insights from the TOPCAT trial. Tang Y, et al, Open Heart 2025. ======

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  * **Proposé le :** 20/03/2026 04:07:10
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===== Résumé et points clés =====

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===== Références de l'article =====

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===== Références =====

~~REFNOTES~~

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